Which of the following, if true, most seriously undermines the advertisement’s argument?

Advertisement: For sinus pain, three out of four hospitals give their patients Novex. So when you want the most effective painkiller for sinus pain, Novex is the one to choose. Which of the following, if true, most seriously undermines the advertisement’s argument?
A. Some competing brands of painkillers are intended to reduce other kinds of pain in addition to sinus pain.
B. Many hospitals that do not usually use Novex will do so for those patients who cannot tolerate the drug the hospitals usually use.
C. Many drug manufacturers increase sales of their products to hospitals by selling these products to the hospitals at the lowest price the manufacturers can afford.
D. Unlike some competing brands of painkillers, Novex is available from pharmacies without a doctor’s prescription.
E. In clinical trials Novex has been found more effective than competing brands of painkillers that have been on the market longer than Novex.

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