Which of the following, if true, would most seriously weaken the conclusion above?

Although perioral dermatitis rashes are believed to be caused by reactions to Sodium Laurel Sulfate (SLS) found in shampoos and other personal care products, instructing patients to eliminate all products with SLS frequently does not stop the perioral dermatitis. Obviously, some other cause of perioral dermatitis besides reactions to SLS must exist.
Which of the following, if true, would most seriously weaken the conclusion above?
A. Many personal care products elicit an allergic skin response only after several days, making it very difficult to observe links between specific products patients use and theperioral dermatitis they develop.
B. Skin allergies affect many people who never develop the symptom of perioral dermatitis.
C. Many patients report that the personal care products that cause them perioral dermatitis are among the products they most enjoy using.
D. Very few patients have allergic skin reactions as children and then live rash-free adult lives once they have eliminated products to which they have been demonstrated to be allergic.
E. Very rarely do personal care products cause patients to suffer a symptom more severe than that of perioral dermatitis rashes.

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